wellness lab

Is Melatonin Safe? Side Effects, Safety for Kids & Pregnancy, and the Right Dosage

By — Sleep Researcher, UCLA •
Short answer: For most healthy adults, melatonin is generally safe when used short-term and at low doses (about 0.5–3 mg). Higher doses raise the chance of side effects (morning drowsiness, headaches, dizziness, nausea). Kids and those who are pregnant/breastfeeding should use melatonin only with clinician guidance.
Is melatonin safe? Nutreska Clinical guide to melatonin safety and side effects

Key Takeaway: Is Melatonin Safe?

  • Yes, generally safe for healthy adults at low doses and short-term.
  • Possible side effects: drowsiness, dizziness, nausea, headaches, vivid dreams.
  • Kids/teens: only under pediatric supervision.
  • Pregnancy/breastfeeding: avoid unless prescribed.
  • Long-term: data is limited—use the lowest effective dose and review with your clinician.

What Is Melatonin & Why Do People Use It?

Melatonin is a hormone from the pineal gland that helps regulate the sleep–wake cycle. Supplemental melatonin (pills, tablets, gummies) mimics the natural signal for sleep. Common reasons to use it:

  • Insomnia or sleep onset issues
  • Jet lag to help re-align circadian rhythm
  • Shift work support
Woman sleeping peacefully in a hotel—melatonin for jet lag support

Melatonin Side Effects (Usually Mild)

  • Daytime drowsiness—more likely with higher doses
  • Headache or dizziness
  • Digestive upset (nausea, cramps)
  • Mood or dream changes (rare)

Tip: minimize effects by starting low (≈1 mg), taking 30–60 minutes before bed, and dimming lights/screens.

Is Melatonin Safe for Kids?

Short-term use may be appropriate under a pediatrician’s guidance, but it should never replace healthy sleep routines. Long-term effects on growth/puberty are still being studied. Infants: always consult a pediatrician.

Melatonin in Pregnancy & Breastfeeding

Melatonin levels naturally rise in pregnancy, but supplement safety data is limited. Most clinicians recommend avoiding melatonin during pregnancy or breastfeeding unless specifically prescribed.

Restful bedroom setting—safe melatonin habits and sleep hygiene

Best Dosage: How Much Melatonin Should You Take?

  • Adults: 0.5–3 mg (up to 5 mg short-term), 30–60 minutes pre-bed.
  • Children: 0.5–3 mg only with pediatric oversight.
  • Jet lag: 2–5 mg at local bedtime for a few nights.

More isn’t better. High doses increase side effects and don’t reliably improve sleep quality.

How to Choose a Quality Melatonin Brand

  • Third-party testing for purity and accurate dosing
  • Clear dose per gummy/tablet; minimal fillers
  • Evidence-based, low-dose formulas with calming botanicals

Is Long-Term Melatonin Use Safe?

Data beyond 6–12 months is limited. Concerns relate to hormone signaling (especially in kids/teens) and potential next-day sedation with higher doses. If using longer-term, review periodically with your clinician and keep the dose as low as possible.

FAQ

Is melatonin addictive?

No—melatonin is not habit-forming. It signals sleep; it doesn’t sedate like prescription hypnotics. Psychological reliance can occur, so pair with solid sleep hygiene.

Can I take melatonin every night?

Many adults use low-dose melatonin nightly for a period without issues. Review ongoing use with your clinician and keep doses low.

When should I take it?

About 30–60 minutes before bedtime. For jet lag or circadian issues, timing may change—follow a plan.

Related: Melatonin Side-EffectsHow Much Melatonin Is Too Much?Insomnia Guide

References & Further Reading

  1. NCCIH. Melatonin: What You Need to Know. 2024. nccih.nih.gov
  2. American Academy of Sleep Medicine. Clinical Practice Guideline... J Clin Sleep Med. 2017;13(2):307–349.
  3. Ferracioli-Oda E, et al. Meta-analysis: Melatonin for Primary Sleep Disorders. PLoS One. 2013;8(5):e63773.
  4. Zhou ES, et al. Safety and Effectiveness of Melatonin in Adults. Nat Sci Sleep. 2022;14:1791–1802.